In 2024, the Wisconsin Sleep Cohort study group was awarded a 5-year grant from the National Institutes of Health. The Sleep and Aerobic Fitness grant is co-led by principal investigators, Dr. Ozioma Okonkwo and Dr. Paul Peppard. We refer to this as the REPLENISH study.
REPLENISH STUDY
Research Focus
This study investigates how sleep and exercise are related to cognitive functioning, brain changes, and mental abilities such as memory, learning, and attention.
Who is Eligible to Participate?
Past participants of Wisconsin Sleep Cohort studies who have completed a previous overnight sleep study and cognitive testing are eligible for this new study. We welcome the participation of ALL eligible volunteers, including those who are experiencing age-related conditions or other health issues.
How to Participate
We are enrolling 300 volunteers from the Wisconsin Sleep Cohort. If you would like to participate, be on the lookout for an invitation letter. We will contact you by mail and follow up with a phone call.
Recruitment and study visits began in August of 2024.
What’s involved?
Participants in this study will have a brain MRI, a blood draw, and they will perform study procedures that will be familiar to our volunteers from past experiences in our studies. For example, we will perform tests of vigilance, cognition, and vision testing. As usual, there are questionnaires about your sleep, health, and health habits. This study does not include an overnight component. All of these protocols will happen at the UW Hospital and Clinics.
For a subset of individuals (80), they will be invited to have a brain PET scan and a Treadmill Testing protocol.
Procedures can be adapted for volunteers with special needs related to age-related,health, or other conditions.