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Leary EB, Watson KT, Ancoli-Israel S, Redline S, Yaffe K, Ravelo LA, Peppard PE, Zou J, Goodman SN, Mignot E, Stone KL. Association of Rapid Eye Movement Sleep With Mortality in Middle-aged and Older Adults. JAMA Neurol. 2020 Jul 6;77(10):1–12. doi: 10.1001/jamaneurol.2020.2108. Epub ahead of print. PMID: 32628261.

Brink-Kjaer A, Olesen AN, Peppard PE, Stone KL, Jennum P, Mignot E, Sorensen HBD. Automatic detection of cortical arousals in sleep and their contribution to daytime sleepiness. Clin Neurophysiol. 2020 Jun;131(6):1187-1203. doi: 10.1016/j.clinph.2020.02.027. Epub 2020 Apr 2. PMID: 32299002.

Carvelli L, Olesen AN, Brink-Kjær A, Leary EB, Peppard PE, Mignot E, Sørensen HBD, Jennum P. Design of a deep learning model for automatic scoring of periodic and non-periodic leg movements during sleep validated against multiple human experts. Sleep Med. 2020 May;69:109-119. doi: 10.1016/j.sleep.2019.12.032. Epub 2020 Jan 23. PMID: 32062037.

Lyu B, Hagen EW, Ravelo LA, Peppard PE. Blood pressure dipping and sleep quality in the Wisconsin Sleep Cohort. J Hypertens. 2020 Mar;38(3):448-455. doi: 10.1097/HJH.0000000000002283. PMID: 31714339.

Plante DT, Hagen EW, Ravelo LA, Peppard PE. Impaired neurobehavioral alertness quantified by the psychomotor vigilance task is associated with depression in the Wisconsin Sleep Cohort study. Sleep Med. 2020 Mar;67:66-70. doi: 10.1016/j.sleep.2019.11.1248. Epub 2019 Dec 4. PMID: 31918119.

Mesas AE, Peppard PE, Hale L, Friedman EM, Nieto FJ, Hagen EW. Individuals’ perceptions of social support from family and friends are associated with lower risk of sleep complaints and short sleep duration. Sleep Health. 2020 Feb;6(1):110-116. doi: 10.1016/j.sleh.2019.08.013. Epub 2019 Nov 16. PMID: 31740375.


Harden CM, Peppard PE, Palta M, Barnet JH, Hale L, Nieto FJ, Hagen EW. One-year changes in self-reported napping behaviors across the retirement transition. Sleep Health. 2019 Dec;5(6):639-646. doi: 10.1016/j.sleh.2019.08.005. Epub 2019 Nov 11. PMID: 31727591.

Mallinson DC, Kamenetsky ME, Hagen EW, Peppard PE. Subjective sleep measurement: comparing sleep diary to questionnaire. Nat Sci Sleep. 2019 Sep 11;11:197-206. doi: 10.2147/NSS.S217867. PMID: 31686932; PMCID: PMC6752706.

Sankari A, Ravelo LA, Maresh S, Aljundi N, Alsabri B, Fawaz S, Hamdon M, Al-Kubaisi G, Hagen E, Badr MS, Peppard P. Longitudinal effect of nocturnal R-R intervals changes on cardiovascular outcome in a community-based cohort. BMJ Open. 2019 Jul 17;9(7):e030559. doi: 10.1136/bmjopen-2019-030559. PMID: 31315880; PMCID: PMC6661586.

Devita M, Peppard PE, Mesas AE, Mondini S, Rusconi ML, Barnet JH, Hagen EW. Associations Between the Apnea-Hypopnea Index During REM and NREM Sleep and Cognitive Functioning in a Cohort of Middle-Aged Adults. J Clin Sleep Med. 2019 Jul 15;15(7):965-971. doi: 10.5664/jcsm.7872. PMID: 31383233; PMCID: PMC6622515.

Canales MT, Hagen EW, Barnet JH, Peppard PE, Derose SF. Response to “Does renal function decline slower in those with sleep apnea?”. Sleep. 2019 Jun 11;42(6):zsz084. doi: 10.1093/sleep/zsz084. PMID: 31184757.

Lacourse K, Delfrate J, Beaudry J, Peppard P, Warby SC. A sleep spindle detection algorithm that emulates human expert spindle scoring. J Neurosci Methods. 2019 Mar 15;316:3-11. doi: 10.1016/j.jneumeth.2018.08.014. Epub 2018 Aug 11. PMID: 30107208; PMCID: PMC6415669.


Stephansen JB, Olesen AN, Olsen M, Ambati A, Leary EB, Moore HE, Carrillo O, Lin L, Han F, Yan H, Sun YL, Dauvilliers Y, Scholz S, Barateau L, Hogl B, Stefani A, Hong SC, Kim TW, Pizza F, Plazzi G, Vandi S, Antelmi E, Perrin D, Kuna ST, Schweitzer PK, Kushida C, Peppard PE, Sorensen HBD, Jennum P, Mignot E. Neural network analysis of sleep stages enables efficient diagnosis of narcolepsy. Nat Commun. 2018 Dec 6;9(1):5229. doi: 10.1038/s41467-018-07229-3. PMID: 30523329; PMCID: PMC6283836.

Mesas AE, Hagen EW, Peppard PE. The bidirectional association between physical activity and sleep in middle-aged and older adults: a prospective study based on polysomnography. Sleep. 2018 Sep 1;41(9):zsy114. doi: 10.1093/sleep/zsy114. PMID: 29860437; PMCID: PMC6132624.

Peppard PE, Hagen EW. Reply to Holley and Phillips: The Next 25 Years of Obstructive Sleep Apnea Epidemiology-Don’t Keep Repeating Past Mistakes. Am J Respir Crit Care Med. 2018 Aug 1;198(3):410-411. doi: 10.1164/rccm.201803-0467LE. PMID: 29596753.

Olesen AN, Jennum P, Peppard P, Mignot E, Sorensen HBD. Deep residual networks for automatic sleep stage classification of raw polysomnographic waveforms. Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:1-4. doi: 10.1109/EMBC.2018.8513080. PMID: 30440296.

Chen H, Cade BE, Gleason KJ, Bjonnes AC, Stilp AM, Sofer T, Conomos MP, Ancoli-Israel S, Arens R, Azarbarzin A, Bell GI, Below JE, Chun S, Evans DS, Ewert R, Frazier-Wood AC, Gharib SA, Haba-Rubio J, Hagen EW, Heinzer R, Hillman DR, Johnson WC, Kutalik Z, Lane JM, Larkin EK, Lee SK, Liang J, Loredo JS, Mukherjee S, Palmer LJ, Papanicolaou GJ, Penzel T, Peppard PE, Post WS, Ramos AR, Rice K, Rotter JI, Sands SA, Shah NA, Shin C, Stone KL, Stubbe B, Sul JH, Tafti M, Taylor KD, Teumer A, Thornton TA, Tranah GJ, Wang C, Wang H, Warby SC, Wellman DA, Zee PC, Hanis CL, Laurie CC, Gottlieb DJ, Patel SR, Zhu X, Sunyaev SR, Saxena R, Lin X, Redline S. Multiethnic Meta-Analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea-related Quantitative Trait Locus in Men. Am J Respir Cell Mol Biol. 2018 Mar;58(3):391-401. doi: 10.1165/rcmb.2017-0237OC. PMID: 29077507; PMCID: PMC5854957.

Olsen M, Schneider LD, Cheung J, Peppard PE, Jennum PJ, Mignot E, Sorensen HBD. Automatic, electrocardiographic-based detection of autonomic arousals and their association with cortical arousals, leg movements, and respiratory events in sleep. Sleep. 2018 Mar 1;41(3):zsy006. doi: 10.1093/sleep/zsy006. PMID: 29329416; PMCID: PMC5914410.

Peppard PE, Hagen EW. The Last 25 Years of Obstructive Sleep Apnea Epidemiology-and the Next 25? Am J Respir Crit Care Med. 2018 Feb 1;197(3):310-312. doi: 10.1164/rccm.201708-1614PP. PMID: 29035088.

Ruoff C, Pizza F, Trotti LM, Sonka K, Vandi S, Cheung J, Pinto S, Einen M, Simakajornboon N, Han F, Peppard P, Nevsimalova S, Plazzi G, Rye D, Mignot E. The MSLT is Repeatable in Narcolepsy Type 1 But Not Narcolepsy Type 2: A Retrospective Patient Study. J Clin Sleep Med. 2018 Jan 15;14(1):65-74. doi: 10.5664/jcsm.6882. PMID: 29198301; PMCID: PMC5734895.

Canales MT, Hagen EW, Barnet JH, Peppard PE, Derose SF. Sleep Apnea and Kidney Function Trajectory: Results From a 20-Year Longitudinal Study of Healthy Middle-Aged Adults. Sleep. 2018 Jan 1;41(1):zsx181. doi: 10.1093/sleep/zsx181. PMID: 29112764; PMCID: PMC5806556.


Owens RL, Gold KA, Gozal D, Peppard PE, Jun JC, Dannenberg AJ, Lippman SM, Malhotra A; UCSD Sleep and Cancer Symposium Group. Sleep and Breathing … and Cancer? Cancer Prev Res (Phila). 2016 Nov;9(11):821-827. doi: 10.1158/1940-6207.CAPR-16-0092. Epub 2016 Sep 7. Erratum in: Cancer Prev Res (Phila). 2017 Jan;10 (1):98. PMID: 27604751; PMCID: PMC5353979.

Koch H, Schneider LD, Finn LA, Leary EB, Peppard PE, Hagen E, Sorensen HBD, Jennum P, Mignot E. Breathing Disturbances Without Hypoxia Are Associated With Objective Sleepiness in Sleep Apnea. Sleep. 2017 Nov 1;40(11):zsx152. doi: 10.1093/sleep/zsx152. PMID: 29029253; PMCID: PMC6251661.

Hale L, Singer L, Barnet JH, Peppard PE, Hagen EW. Associations Between Midlife Insomnia Symptoms and Earlier Retirement. Sleep Health. 2017 Jun;3(3):170-177. doi: 10.1016/j.sleh.2017.03.003. Epub 2017 Apr 1. PMID: 28526254.

Olsen AV, Stephansen J, Leary E, Peppard PE, Sheungshul H, Jennum PJ, Sorensen H, Mignot E. Diagnostic value of sleep stage dissociation as visualized on a 2-dimensional sleep state space in human narcolepsy. J Neurosci Methods. 2017 Apr 15;282:9-19. doi: 10.1016/j.jneumeth.2017.02.004. Epub 2017 Feb 20. PMID: 28219726.

Mirer AG, Young T, Palta M, Benca RM, Rasmuson A, Peppard PE. Sleep-disordered breathing and the menopausal transition among participants in the Sleep in Midlife Women Study. Menopause. 2017 Feb;24(2):157-162. doi: 10.1097/GME.0000000000000744. PMID: 27760083; PMCID: PMC5266663.

Plante DT, Finn LA, Hagen EW, Mignot E, Peppard PE. Longitudinal associations of hypersomnolence and depression in the Wisconsin Sleep Cohort Study. J Affect Disord. 2017 Jan 1;207:197-202. doi: 10.1016/j.jad.2016.08.039. Epub 2016 Oct 3. PMID: 27723544; PMCID: PMC5107142.



Gunnarsson SI, Peppard PE, Korcarz CE, Barnet JH, Hagen EW, Hla KM, Palta M, Young T, Stein JH. Minimal nocturnal oxygen saturation predicts future subclinical carotid atherosclerosis: the Wisconsin sleep cohort. J Sleep Res. 2015 Dec;24(6):680-6. doi: 10.1111/jsr.12321. Epub 2015 Jun 22. PMID: 26096939; PMCID: PMC4626295.

Christensen JA, Munk EG, Peppard PE, Young T, Mignot E, Sorensen HB, Jennum P. The diagnostic value of power spectra analysis of the sleep electroencephalography in narcoleptic patients. Sleep Med. 2015 Dec;16(12):1516-27. doi: 10.1016/j.sleep.2015.09.005. Epub 2015 Sep 15. PMID: 26611950.

Christensen JA, Carrillo O, Leary EB, Peppard PE, Young T, Sorensen HB, Jennum P, Mignot E. Sleep-stage transitions during polysomnographic recordings as diagnostic features of type 1 narcolepsy. Sleep Med. 2015 Dec;16(12):1558-66. doi: 10.1016/j.sleep.2015.06.007. Epub 2015 Jul 7. PMID: 26299470.

Mokhlesi B, Hagen EW, Finn LA, Hla KM, Carter JR, Peppard PE. Obstructive sleep apnoea during REM sleep and incident non-dipping of nocturnal blood pressure: a longitudinal analysis of the Wisconsin Sleep Cohort. Thorax. 2015 Nov;70(11):1062-9. doi: 10.1136/thoraxjnl-2015-207231. Epub 2015 Aug 25. PMID: 26307037.

Li J, Moore H 4th, Lin L, Young T, Finn L, Peppard PE, Mignot E. Association of low ferritin with PLM in the Wisconsin Sleep Cohort. Sleep Med. 2015 Nov;16(11):1413-1418. doi: 10.1016/j.sleep.2015.05.015. Epub 2015 Jun 18. PMID: 26498245.

Mirer AG, Peppard PE, Palta M, Benca RM, Rasmuson A, Young T. Menopausal hormone therapy and sleep-disordered breathing: evidence for a healthy user bias. Ann Epidemiol. 2015 Oct;25(10):779-84.e1. doi: 10.1016/j.annepidem.2015.07.004. Epub 2015 Aug 6. PMID: 26358364; PMCID: PMC5645789.

Gottlieb DJ, Hek K, Chen TH, Watson NF, Eiriksdottir G, Byrne EM, Cornelis M, Warby SC, Bandinelli S, Cherkas L, Evans DS, Grabe HJ, Lahti J, Li M, Lehtimäki T, Lumley T, Marciante KD, Pérusse L, Psaty BM, Robbins J, Tranah GJ, Vink JM, Wilk JB, Stafford JM, Bellis C, Biffar R, Bouchard C, Cade B, Curhan GC, Eriksson JG, Ewert R, Ferrucci L, Fülöp T, Gehrman PR, Goodloe R, Harris TB, Heath AC, Hernandez D, Hofman A, Hottenga JJ, Hunter DJ, Jensen MK, Johnson AD, Kähönen M, Kao L, Kraft P, Larkin EK, Lauderdale DS, Luik AI, Medici M, Montgomery GW, Palotie A, Patel SR, Pistis G, Porcu E, Quaye L, Raitakari O, Redline S, Rimm EB, Rotter JI, Smith AV, Spector TD, Teumer A, Uitterlinden AG, Vohl MC, Widen E, Willemsen G, Young T, Zhang X, Liu Y, Blangero J, Boomsma DI, Gudnason V, Hu F, Mangino M, Martin NG, O’Connor GT, Stone KL, Tanaka T, Viikari J, Gharib SA, Punjabi NM, Räikkönen K, Völzke H, Mignot E, Tiemeier H. Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study. Version 2. Mol Psychiatry. 2015 Oct;20(10):1232-9. doi: 10.1038/mp.2014.133. Epub 2014 Dec 2. PMID: 25469926; PMCID: PMC4430294.

Wendt SL, Welinder P, Sorensen HB, Peppard PE, Jennum P, Perona P, Mignot E, Warby SC. Inter-expert and intra-expert reliability in sleep spindle scoring. Clin Neurophysiol. 2015 Aug;126(8):1548-56. doi: 10.1016/j.clinph.2014.10.158. Epub 2014 Nov 10. PMID: 25434753; PMCID: PMC4426257.

Teodorescu M, Barnet JH, Hagen EW, Palta M, Young TB, Peppard PE. Association between asthma and risk of developing obstructive sleep apnea. JAMA. 2015 Jan 13;313(2):156-64. doi: 10.1001/jama.2014.17822. Erratum in: JAMA. 2015 Jul 7;314(1):86. PMID: 25585327; PMCID: PMC4334115.

Hla KM, Young T, Hagen EW, Stein JH, Finn LA, Nieto FJ, Peppard PE. Coronary heart disease incidence in sleep disordered breathing: the Wisconsin Sleep Cohort Study. Sleep. 2015 May 1;38(5):677-84. doi: 10.5665/sleep.4654. PMID: 25515104; PMCID: PMC4402672.


Moore H 4th, Leary E, Lee SY, Carrillo O, Stubbs R, Peppard P, Young T, Widrow B, Mignot E. Design and validation of a periodic leg movement detector. PLoS One. 2014 Dec 9;9(12):e114565. doi: 10.1371/journal.pone.0114565. Erratum in: PLoS One. 2015;10(9):e0138205. PMID: 25489744; PMCID: PMC4260847.

Mokhlesi B, Finn LA, Hagen EW, Young T, Hla KM, Van Cauter E, Peppard PE. Obstructive sleep apnea during REM sleep and hypertension. Results of the Wisconsin Sleep Cohort. Am J Respir Crit Care Med. 2014 Nov 15;190(10):1158-67. doi: 10.1164/rccm.201406-1136OC. PMID: 25295854; PMCID: PMC4299639.

Gunnarsson SI, Peppard PE, Korcarz CE, Barnet JH, Aeschlimann SE, Hagen EW, Young T, Hla KM, Stein JH. Obstructive sleep apnea is associated with future subclinical carotid artery disease: thirteen-year follow-up from the Wisconsin sleep cohort. Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2338-42. doi: 10.1161/ATVBAHA.114.303965. Epub 2014 Sep 4. PMID: 25189572; PMCID: PMC4259877.

Korcarz CE, Stein JH, Peppard PE, Young TB, Barnet JH, Nieto FJ. Combined effects of sleep disordered breathing and metabolic syndrome on endothelial function: the Wisconsin Sleep Cohort study. Sleep. 2014 Oct 1;37(10):1707-13. doi: 10.5665/sleep.4086. PMID: 25197813; PMCID: PMC4173927.

Moore H 4th, Winkelmann J, Lin L, Finn L, Peppard P, Mignot E. Periodic leg movements during sleep are associated with polymorphisms in BTBD9, TOX3/BC034767, MEIS1, MAP2K5/SKOR1, and PTPRD. Sleep. 2014 Sep 1;37(9):1535-42. doi: 10.5665/sleep.4006. PMID: 25142570; PMCID: PMC4153066.

Goldbart A, Peppard P, Finn L, Ruoff CM, Barnet J, Young T, Mignot E. Narcolepsy and predictors of positive MSLTs in the Wisconsin Sleep Cohort. Sleep. 2014 Jun 1;37(6):1043-51. doi: 10.5665/sleep.3758. PMID: 24882899; PMCID: PMC4015378.

Warby SC, Wendt SL, Welinder P, Munk EG, Carrillo O, Sorensen HB, Jennum P, Peppard PE, Perona P, Mignot E. Sleep-spindle detection: crowdsourcing and evaluating performance of experts, non-experts and automated methods. Version 2. Nat Methods. 2014 Apr;11(4):385-92. doi: 10.1038/nmeth.2855. Epub 2014 Feb 23. PMID: 24562424; PMCID: PMC3972193.






Peppard PE, Ward NR, Morrell MJ. The impact of obesity on oxygen desaturation during sleep-disordered breathing. Am J Respir Crit Care Med. 2009 Oct 15;180(8):788-93. doi: 10.1164/rccm.200905-0773OC. Epub 2009 Jul 30. PMID: 19644043; PMCID: PMC2778152.

Young T, Palta M, Dempsey J, Peppard PE, Nieto FJ, Hla KM. Burden of sleep apnea: rationale, design, and major findings of the Wisconsin Sleep Cohort study. WMJ. 2009 Aug;108(5):246-9. PMID: 19743755; PMCID: PMC2858234.

Bautista LE, Stein JH, Morgan BJ, Stanton N, Young T, Nieto FJ. Association of blood and hair mercury with blood pressure and vascular reactivity. WMJ. 2009 Aug;108(5):250-2. PMID: 19743756; PMCID: PMC4593490.

Hallmayer J, Faraco J, Lin L, Hesselson S, Winkelmann J, Kawashima M, Mayer G, Plazzi G, Nevsimalova S, Bourgin P, Hong SC, Honda Y, Honda M, Högl B, Longstreth WT Jr, Montplaisir J, Kemlink D, Einen M, Chen J, Musone SL, Akana M, Miyagawa T, Duan J, Desautels A, Erhardt C, Hesla PE, Poli F, Frauscher B, Jeong JH, Lee SP, Ton TG, Kvale M, Kolesar L, Dobrovolná M, Nepom GT, Salomon D, Wichmann HE, Rouleau GA, Gieger C, Levinson DF, Gejman PV, Meitinger T, Young T, Peppard P, Tokunaga K, Kwok PY, Risch N, Mignot E. Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nat Genet. 2009 Jun;41(6):708-11. doi: 10.1038/ng.372. Epub 2009 May 3. Erratum in: Nat Genet. 2009 Jul;41(7):859. Hong, Sheng Seung-Chul [corrected to Hong, Seung-Chul]. PMID: 19412176; PMCID: PMC2803042.

Young T. Rationale, design and findings from the Wisconsin Sleep Cohort Study: Toward understanding the total societal burden of sleep disordered breathing. Sleep Med Clin. 2009 Mar 1;4(1):37-46. doi: 10.1016/j.jsmc.2008.11.003. PMID: 20161300; PMCID: PMC2699290.